Publications by authors named "A Kritikos"
Secondary peritonitis with intra-abdominal abscesses (IAA) is difficult to treat because of the supposed low rate of penetration of antimicrobial drugs at the site of infection. However, clinical data about the actual bioavailability of antimicrobial drugs in IAA are scarce. This prospective observational study aimed at assessing the drug penetration in IAA of the antibiotics (piperacillin-tazobactam, carbapenems) and antifungals (fluconazole, echinocandins) that are usually recommended for the treatment of intra-abdominal infections.
View Article and Find Full Text PDFCrossmodal correspondence of elevation/pitch and size/pitch is driven by real-world features.
Atten Percept Psychophys
November 2024
Crossmodal correspondences are consistent associations between sensory features from different modalities, with some theories suggesting they may either reflect environmental correlations or stem from innate neural structures. This study investigates this question by examining whether retinotopic or representational features of stimuli induce crossmodal congruency effects. Participants completed an auditory pitch discrimination task paired with visual stimuli varying in their sensory (retinotopic) or representational (scene integrated) nature, for both the elevation/pitch and size/pitch correspondences.
View Article and Find Full Text PDF[Community-acquired Bacteremia: when should endocarditis be suspected?].
Rev Med Suisse
October 2024
Article Synopsis
- * It highlights that community-acquired bacteremia poses a greater IE risk compared to bacteremia acquired in hospitals, and that certain factors like having implantable cardiovascular devices or a history of IE increase this risk.
- * The article also mentions the development of risk stratification systems to help doctors decide when to perform echocardiography for patients with specific bacteria like S. aureus, and proposes an evaluation algorithm based on these systems.
Purpose: Medical cannabis use is rising with limited high-quality clinical trial data to guide dosing. This study relies on real-world, longitudinal medical cannabis purchase data to provide information on Δ-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) dosing trends for patients with qualifying medical conditions.
Methods: A retrospective study of purchases by 16,727 patients obtaining medical cannabis from dispensaries located in New York between 2016 and 2019, recorded in point-of-sale data.
Article Synopsis
- Vertebrate sexual dimorphism, traditionally linked to the type of gonads (testes or ovaries) and their hormone production, is now shown to also be influenced by sex chromosomes (XX or XY).
- Using the Four-Core Genotypes (FCG) mouse model, the study reveals that both gonads and sex chromosomes affect the musculoskeletal system's development, with notable differences becoming more pronounced in older mice.
- Findings indicate that while gonadal sex plays a significant role in musculoskeletal traits, sex chromosomes contribute meaningfully to differences in body composition and bone strength, particularly as the mice mature.