Publications by authors named "A Kravchuk"
Article Synopsis
- The study explores the use of Large Language Models (LLMs) to enhance decision-making in urological cancer treatment, aiming to compare their recommendations with those of traditional tumor boards.
- It validates two scoring scales, the System Causability Scale (SCS) and its modified version (mSCS), showing they have strong reliability and internal consistency for future trials.
- The upcoming CONCORDIA trial will formally test LLM recommendations against multidisciplinary tumor board recommendations across 110 urological cancer scenarios.
Objectives: To compare Uromonitor® (U-Monitor Lda, Porto, Portugal), a multitarget DNA assay that detects mutated proto-oncogenes (telomerase reverse transcriptase [TERT], fibroblast growth factor receptor 3 [FGFR-3], Kirsten rat sarcoma viral oncogene homologue [KRAS]), with urine cytology in the urine-based diagnosis of urothelial carcinoma of the bladder (UCB) within a multicentre real-world setting.
Patients And Methods: This multicentre, prospective, double-blind study was conducted across four German urological centres from 2019 to 2024. We evaluated the diagnostic performance of Uromonitor compared to urine cytology in a cohort of patients with UCB and in healthy controls within a real-world setting.
Article Synopsis
- A collective use center is a specialized organization that provides access to unique biological resources, particularly in the field of human materials like tumor tissues, despite ethical and legal challenges.
- The Bioresource collection center at the Burdenko Neurosurgical Center has been operational since October 2022, aiming to meet the growing demand for human biological resources in various research fields.
- An analysis of 275 publications showed that many biobanks, while not officially labeled as collective use centers, still play a significant role in supplying biological materials for research on central nervous system tumors.
This study is aimed at investigating epileptic seizures, one of the consequences of traumatic brain injury (TBI). Immediate and early post-traumatic seizures, as well as late post-traumatic epileptic seizures or post-traumatic epilepsy, can have different pathogenetic bases. The following key risk factors associated with post-traumatic epilepsy are known: duration of unconsciousness, gunshot wounds, intracranial hemorrhage, diffuse axonal injury, prolonged (more than 3 days) post-traumatic amnesia, acute subdural hematoma with surgical evacuation, immediate and early post-traumatic epileptic seizures, fracture of the skull bones.
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