Publications by authors named "A Krasinskas"
Diagnostic Pearls and Pitfalls in the Evaluation of Small Biopsies From the Bile Duct and Ampulla.
Arch Pathol Lab Med
November 2024
Article Synopsis
- Evaluating biopsies from the bile duct and ampullary regions is complicated due to their small size and potential for misleading features, where benign changes may look like cancer.
- The objective is to highlight important diagnostic tips and common mistakes when interpreting these challenging biopsies.
- Pathologists must strive for accurate diagnoses using diagnostic clues, additional tests, and awareness of potential pitfalls, especially since these biopsies are obtained through invasive procedures.
Background: The information on the clinicopathologic/outcome differences between ampullary adenocarcinoma (AC) and pancreatic adenocarcinoma (PC) has been conflicting to the extent that it still is questioned whether ACs need to be recognized separately from PCs.
Methods: The characteristics of 413 ACs were compared with those of 547 PCs.
Results: The ACs had a better prognosis than the PCs (5-year survival, 57 % vs 23 %; p < 0.
Background: Grade 1/2 PanNETs are mostly managed similarly, typically without any adjunct treatment with the belief that their overall metastasis rate is low. In oncology literature, Ki67-index of 10% is increasingly being used as the cutoff in stratifying patients to different protocols, although there are no systematic pathology-based studies supporting this approach.
Methods: Ki67-index was correlated with clinicopathologic parameters in 190 resected PanNETs.