Multimodal management of breast architectural distortion: an analytical literature review.

Objective: Aim: The objective of this literature review was to determine the optimal diagnostic algorithm for breast cancer detection associated with architectural distortion.

Patients And Methods: Materials and Methods: The Pubmed, Google Scholar, Web of Science, and Scopus databases was used to search for materials on architectural distortion, associated pathologies, and radiological imaging methods.

Conclusion: Conclusions: Architectural distortions may represent both benign and malignant pathology, but ultrasound, magnetic resonance, and roentgenological signs may not always with conf i dence determine the etiology of these changes.

Covalent functionalization by using blue light activated radicals: on the reaction mechanisms of arylazo sulfone binding on graphene.

Covalent functionalization of graphene presents a pivotal strategy to enhance its surface properties and overcome inherent chemical inertness. While diazonium salts have been extensively utilized for this purpose, their limitations necessitate exploration of alternative approaches. Arylazo sulfones, such as diazonium salt derivatives serving as chromophores, offer a promising solution, enabling photochemical reactions under visible light.

Graphene oxide electrodes enable electrical stimulation of distinct calcium signalling in brain astrocytes.

Astrocytes are responsible for maintaining homoeostasis and cognitive functions through calcium signalling, a process that is altered in brain diseases. Current bioelectronic tools are designed to study neurons and are not suitable for controlling calcium signals in astrocytes. Here, we show that electrical stimulation of astrocytes using electrodes coated with graphene oxide and reduced graphene oxide induces respectively a slow response to calcium, mediated by external calcium influx, and a sharp one, exclusively due to calcium release from intracellular stores.