Publications by authors named "A Kouketsu"
Background: We aimed to construct an artificial intelligence-based model for detecting oral cancer and dysplastic leukoplakia using oral cavity images captured with a single-lens reflex camera.
Subjects And Methods: We used 1043 images of lesions from 424 patients with oral squamous cell carcinoma (OSCC), leukoplakia, and other oral mucosal diseases. An object detection model was constructed using a Single Shot Multibox Detector to detect oral diseases and their locations using images.
Article Synopsis
- - Mixed neuroendocrine-non-neuroendocrine neoplasms (MiNENs) are rare tumors containing both neuroendocrine and non-neuroendocrine elements, recently recognized in WHO classifications, but are particularly uncommon in the head and neck region.
- - A 64-year-old male patient presented with a primary oral MiNEN on the lower gingiva, initially suspected as neuroendocrine carcinoma (NEC), and subsequently underwent partial mandibulectomy which revealed distinct NEC and squamous cell carcinoma (SCC) components.
- - The patient has remained free of recurrence or metastasis for 6 years post-surgery, and a review of literature identified five other relevant cases,
Microvascular reconstruction for oral cancer in older adult patients: the impact of age on surgical outcomes.
Oral Surg Oral Med Oral Pathol Oral Radiol
January 2024
Objective: Flap complications continue to be a challenge in microsurgical reconstruction for older adults. We aimed to evaluate the impact of age on surgical outcomes after microvascular reconstruction.
Study Design: We retrospectively investigated 103 patients with oral squamous cell carcinoma who had undergone microvascular reconstruction surgery to compare microsurgical reconstruction, common postoperative complications, and flap success rates in geriatric (>75 years) and non-geriatric (<75 years) patients.
Sirtuins (SIRTs) are a family of proteins involved in the metabolic process responsible for extending the lifespan. The role of SIRT1, 6, and 7 in oral squamous cell carcinoma (OSCC) and oral leukoplakia (OLP), one of its precursors, is still elusive. In this study, 82 OLP and 77 OSCC were immunohistochemically examined for SIRT1, 6, and 7.
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