Publications by authors named "A Kostadinova"
The increased life expectancy of PLHIV (People Living with HIV) and the successful highly combined antiretroviral therapy (cART) poses new clinical challenges regarding aging and its co-morbid condition. It is commonly believed that HIV infection "accelerates" aging. Human immunodeficiency virus type 1 (HIV-1) infection is characterized by inflammation and immune activation that persists despite cART, and that may contribute to the development of co-morbid conditions.
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- This study explores how nanomaterials, specifically chitosan (CS) and its composites, affect the organization and morphology of cell membrane lipids under different conditions.
- Researchers investigated interactions between these nanomaterials and various lipid mixtures that simulate different membrane phases.
- The results reveal that CS nanomaterials enhance lipid order and affect vesicle properties, leading to changes like vesicle adhesion, fusion, and shrinking, particularly in fluid membrane phases.
The platyhelminth class Trematoda comprises two subclasses with largely disparate species diversity, with the small Aspidogastrea with c.80 species and the speciose Digenea with c.18,000 species, which has attracted much effort towards our understanding of evolutionary relationships among suprageneric taxa.
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- A study conducted on mononchid nematodes in various riparian habitats in Bulgaria identified four distinct species based on morphological and genetic data, confirming their status as unique species.
- The research included detailed descriptions, measurements, and the first taxonomically verified genetic sequences for several nematode species, enhancing understanding of their diversity.
- Phylogenetic analyses revealed limitations of using the 18S rRNA gene for species delimitation in certain species complexes, while supporting the monophyly of specific genera and providing a key for identifying 31 recognized species.
Exploring the mechanism underlying the antifungal activity of chitosan-based ZnO, CuO, and SiO nanocomposites as nanopesticides against Fusarium solani and Alternaria solani.
Int J Biol Macromol
May 2024
Chitosan-based nanocomposites (CS NCs) are gaining considerable attention as multifaceted antifungal agents. This study investigated the antifungal activity of NCs against two phytopathogenic strains: Fusarium solani (F. solani) and Alternaria solani (A.
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