Publications by authors named "A Korzeniecka-Kozerska"
Article Synopsis
- Neurogenic bladder in children with myelomeningocele (MMC) increases the risk of chronic kidney disease, and this study examines the accuracy of GFR markers, Cystatin C (CysC) and creatinine, in this context.
- *Forty children participated, undergoing tests for serum creatinine, CysC, and body composition via bioelectrical impedance analysis (BIA) to assess the relationship between body fat and kidney function.
- *Findings showed that CysC provided a more accurate GFR estimate than creatinine and highlighted that BIA is a better indicator of obesity than traditional BMI, emphasizing the need to consider body fat in assessing renal health in MMC patients.*
Background: Children with spina bifida (SB) face an elevated risk of obesity, which necessitates precise methods for assessing body composition to ensure effective weight management. Conventional measures like BMI are inadequate for this population because of variations in growth patterns and skeletal structure. Bioelectrical impedance analysis (BIA) is a method that offers a clearer picture of body composition, yet its use in children with SB remains underexplored.
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- - The article investigates the urinary levels of liver-type fatty acid-binding protein (uL-FABP) as a biomarker for detecting tubular damage in children with neurogenic bladder (NB) through a study involving 42 children with NB and 18 healthy children.
- - The study used ELISA methods to measure uL-FABP concentrations and examined various factors such as age, sex, and renal function but found that the differences in uL-FABP/creatinine ratios between the groups were not statistically significant.
- - It concluded that uL-FABP could be a potential biomarker of tubular damage in NB children, especially in those with proteinuria and a history of high-grade vesicoureteral reflux (
This article aims to explore changes in urinary concentrations of selected neurotrophins in the course of TENS therapy in children with overactive bladder (OAB). A two-group open-label prospective study was conducted. The intervention group comprised 30 children aged between 5 and 12 years old with OAB refractory to conservative therapy.
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- The study investigates the potential use of two proteins, NGAL and KIM-1, as early biomarkers of renal damage in children with neurogenic bladder (NB) compared to healthy children.
- It involves a prospective analysis of 58 children with NB and 25 healthy controls, measuring the urinary levels of NGAL and KIM-1 along with various health parameters.
- The findings show that uNGAL levels were significantly higher in the NB group, suggesting it may serve as a valuable indicator of tubular injury in these patients, while uKIM-1 did not show significant differences.