Publications by authors named "A Koryllou"
Disease evolution in systemic juvenile idiopathic arthritis: an international, observational cohort study through JIRcohort.
Pediatr Rheumatol Online J
September 2023
Background: Systemic juvenile idiopathic arthritis (systemic JIA) is a severe disease with both systemic and joint inflammation. This study aims to identify predictors of disease evolution within the systemic JIA population enrolled in the Juvenile Inflammatory Rheumatism cohort (JIRcohort).
Methods: Observational patient cohort study with 201 recruited children from 4 countries (3 European, 1 North Africa) from 2005 until 2019, using retrospectively (2005-2015) and prospectively (2015-2019) routine care collected data.
Chronic nonbacterial osteomyelitis (CNO) is an auto-inflammatory bone disorder with a wide spectrum of clinical manifestations, from unifocal to multifocal lesions. When it manifests with multifocal lesions, it is also referred to as chronic recurrent multifocal osteomyelitis (CRMO). CNO/CRMO can affect all age groups, with the pediatric population being the most common.
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- - The study aimed to explore the demographics and underlying causes of pediatric uveitis over a 20-year period at a Swiss eye hospital, focusing on patients under 16 years old.
- - Out of 2846 uveitis cases examined, 317 (11.1%) were children, with a median onset age of 8.9 years; anterior uveitis was the most common type observed in these patients.
- - The findings indicated that 34% of cases were linked to systemic inflammatory diseases, with juvenile idiopathic arthritis being the leading cause, while 24% had an infectious origin, which is notably higher than what's seen in adult patients.