Publications by authors named "A Korde"
Article Synopsis
- CRISPR/Cas acts like molecular scissors for precise gene editing using mechanisms like non-homologous end joining (NHEJ) or homology-directed repair (HDR), with various Cas effectors available for different applications.
- SpCas9 is the most studied version, recognized as a breakthrough for correcting genetic mutations, while newer variants like Cas12 and Cas13 are noted for their specific abilities to recognize and cleave target nucleic acids.
- The combination of CRISPR technology, diagnostics, and nanotechnology has led to the development of advanced biosensing systems capable of providing quantitative fluorescent signals for diagnostic purposes.
This meeting report summarizes a consultants meeting that was held at International Atomic Energy Agency Headquarters, Vienna, in July 2022 to provide an update on the development of multimodality imaging by combining nuclear medicine imaging agents with other nonradioactive molecular probes and/or biomedical imaging techniques.
View Article and Find Full Text PDFTheranostics has become a major area of innovation and progress in cancer care over the last decade. In view of the introduction of approved therapeutics in neuroendocrine tumours and prostate cancer in the last 10 years, the ability to provide access to these treatments has emerged as a key factor in ensuring global benefits from this cancer therapy approach. In this Series paper we explore the issues that affect access to and availability of theranostic radiopharmaceuticals, including supply and regulatory issues that might affect the availability of theranostic treatments for patients with cancer.
View Article and Find Full Text PDFArticle Synopsis
- * The rapid advancement in diagnostic and therapeutic radiopharmaceuticals, particularly in oncology, presents exciting opportunities but also challenges, like inadequate infrastructure for production and distribution.
- * A critical challenge is ensuring equitable access to these innovations, which requires developing a trained workforce across varying income levels in different countries.
Article Synopsis
- This paper is the first in a series about theranostics, which is a way to use special medicines to help treat cancer.
- It talks about new and cool discoveries in making these medicines and using smart technology to improve them.
- The authors also mention some problems that need to be solved to make these cancer treatments even better in the future.