Publications by authors named "A Koning"

Knowledge of embryonic body posture as a reflection of neurodevelopment is limited. Here, we investigate embryonic body posture, preference, symmetry, and lateralization during periods of rest using virtual reality (VR) and four-dimensional (4D) ultrasound techniques to enhance our knowledge of neurodevelopment. It is hypothesized that lateralization and asymmetry in embryonic posture are absent.

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Study Objective: Essure is a hysteroscopic sterilization device that has been used in the Netherlands since 2003. Essure has received a lot of publicity due to many reported symptoms associated with the device. Because of this, increasing numbers of patients requested surgical removal of Essure devices.

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  • Hypertensive disorders of pregnancy (HDP) are major contributors to complications in pregnancy, prompting research into the role of maternal tryptophan metabolites in placental health and development.
  • The study involved 911 women and assessed serum tryptophan metabolites early in pregnancy, analyzing their relationships with placental volume and vascular development, as well as odds of developing HDP.
  • Findings showed that higher kynurenine levels negatively impacted placental development, while increased levels of 5-hydroxytryptophan were linked to higher risks of early pregnancy hypertension and preeclampsia.
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  • A study examined the emotional and skin-related symptoms in five patients with cutaneous T-cell lymphoma undergoing glucocorticoid treatment, finding that emotional disturbances often accompany this therapy.
  • Results showed that as treatment progressed, positive emotions declined, leading to increased irritation and itchy skin the following day.
  • The findings suggest that reduced positive emotions at the end of glucocorticoid treatment may be linked to lower energy and motivation, potentially worsening skin-related issues.
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Background & Aims: The quantity and quality of maternal nutrition in the periconception period is an important determinant for embryonic and foetal development and subsequent pregnancy course and outcome. The intake of ultra-processed foods (UPF) has increased worldwide and adverse health outcomes have been reported. However, the impact of UPF intake on the placenta, essential for prenatal nourishment, is unknown.

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