Receptor-Binding Cancer Antigen Expression in Thyroid Neoplasms: A Retrospective Study.

Receptor-binding cancer antigen (RCAS1) is a membrane protein, regarded as a tumor-associated antigen. Cancer cells evade immune response with RCAS1 up-regulation, inducing apoptosis to tumor infiltrating lymphocytes. Thyroid cancer incidence is rising and its accurate diagnosis in early stage is targeted.

Survivin expression in hepatocellular carcinoma. Correlation with clinicopathological characteristics and overall survival.

Purpose: Survivin expression is a potential prognostic indicator in various carcinomas. The prognostic value of Survivin for survival in hepatocellular carcinoma, (HCC) however, remains controversial. The aim of the study is to examine the expression of the inhibitor of apoptosis Survivin in HCC and investigate the correlation with the clinic-pathologic characteristics and overall survival (OS) following surgical resection.

Immunohistochemical expression patterns of S100, synaptophysin, chromogranin A and neuron specific enolase in predicting malignant behaviour in paragangliomas.

Purpose: The purpose of this study was to evaluate the role of immunohistochemical markers in the prediction of malignancy in paragangliomas.

Methods: Our institute's patient records between 1990-2012 were retrieved in order to identify patients who were treated for paragangliomas. Size and location of the tumour, existence of concurrent metastatic disease, patient demographics and survival were recorded.

Survivin expression as an independent predictor of overall survival in pancreatic adenocarcinoma.

Context: Survivin is an antiapoptotic protein with a role in tumorigenesis and suggested prognostic value in several proliferative diseases.

Aims: This study aimed to examine the role of survivin as a prognostic marker in pancreatic adenocarcinoma (PDAC).

Settings And Design: Fifty-one specimens of PDAC were assessed for survivin expression by immunohistochemistry.

Prognostic significance of EGFR and COX-2 expression in colorectal cancer and their association. A study in Greek population.

Purpose: Colon cancer is one of the most common malignancies. Various prognostic markers have been proposed and individualized treatment strategies have been adapted according to tumor molecular and genetic characteristics. The purpose of the present study was to retrospectively analyze a possible association between the expression of COX- 2 and EGFR and clinical and histopathological factors of patients undergoing colon surgery in a Greek population.