Publications by authors named "A Kogure"
Background And Aim: Werner syndrome (WS) is an autosomal recessive, adult-onset, progeroid syndrome caused by mutations. As refractory skin ulcers significantly affect the quality of life of patients with WS, this study identified ulcer risk factors and assessed prevention methods.
Methods: We analyzed the data of 51 patients with WS enrolled in the Japanese Werner Syndrome Registry between 2016 and 2022.
Aim: Nocturia impairs the quality of life in patients with type 2 diabetes mellitus. Although sodium glucose co-transporter 2 inhibitors (SGLT2i) such as tofogliflozin increase urine volume, their impact on nocturia, in conjunction with dietary salt restriction, is less clear.
Materials And Methods: This multicenter, open-label, randomized, parallel-group trial included 80 subjects with type 2 diabetes and nocturia.
Article Synopsis
- A study investigated the link between short sleep duration and the development of non-alcoholic fatty liver disease (NAFLD) among 1,862 Japanese adults who were initially free of the condition.
- Over a median follow-up of 41 months, it was found that 25.9% of participants developed NAFLD, with the highest rates among women sleeping less than 6 hours per night.
- The results indicated that women with short sleep duration had a higher risk of developing NAFLD, suggesting that getting enough sleep may help prevent this condition.
Background And Aim: Equol is a metabolite of soy isoflavone and has estrogenic activity. The incidence of non-alcoholic fatty liver disease (NAFLD) increases after menopause in women, which is thought to result in a decrease in estrogen. This study aimed to evaluate the association between equol and NAFLD.
View Article and Find Full Text PDFBackground: The difference between Young's moduli of the femur and the stem causes stress shielding (SS). TiNbSn (TNS) stem has a low Young's modulus and strength with gradient functional properties during the change in elastic modulus with heat treatment. The aim of this study was to investigate the inhibitory effect of TNS stems on SS and their clinical outcomes compared to conventional stems.
View Article and Find Full Text PDF