Publications by authors named "A Killinger"

Article Synopsis
  • Hydroxyapatite (HAp) coatings are used on bone implants to enhance biocompatibility and promote bone growth, but they can still lead to infections.
  • This study explored the use of high-velocity suspension flame spraying (HVSFS) to create thin HAp coatings and tested the effects of varying gas parameters and copper (Cu) additions on their properties and effectiveness.
  • Results indicated that using medium gas parameters and adding 1 wt.% Cu provided a good balance between antibacterial properties and biocompatibility, effectively reducing bacterial counts while limiting cytotoxic effects.
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Article Synopsis
  • Prosthesis loosening is a common implant failure caused by insufficient bonding between the implant and surrounding bone, often compounded by bacterial infection and biofilm.
  • Using bioconductive and biodegradable calcium phosphate (CaP) coatings with incorporated antibacterial agents can enhance both bone integration and combat bacterial growth.
  • This study focuses on creating Cu-doped CaP coatings with better porosity and antibacterial properties, showing good biocompatibility and effective antimicrobial action against various bacterial strains.
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High-velocity oxygen fuel (HVOF) spraying is a promising technique for depositing protective coatings. The performances of HVOF-sprayed coatings are affected by in-flight particle properties, such as temperature and velocity, that are controlled by the spraying parameters. However, obtaining the desired coatings through experimental methods alone is challenging, owing to the complex physical and chemical processes involved in the HVOF approach.

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In the present work, we test four thin coatings for titanium implants, namely, bioglass, GB14, Beta-Tricalciumphosphate (β-TCP) and hydroxyapatite (HA) with and without incorporated copper ions for their osteointegrative capacity. A rabbit drill hole model for time intervals up to 24 weeks was used in this study. Implant fixation was evaluated by measuring shear strength of the implant/bone interface.

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The main target of the present research was a full assessment of the toxicity effects and biocompatibility of a Ti/Al-alloy device coated with biogenic hydroxyapatite (bHA) when implanted in dogs in comparison with those of an uncoated Ti/Al-alloy device. The coating of the alloy was carried out using controlled high-velocity suspension flame spray (HVSFS) technique. Both coated and uncoated devices were implanted in dogs' femur bones for different time periods (45 days and 90 days).

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