Publications by authors named "A Khamooshian"
Objective: Demonstrate that regional geometric differences exist between regurgitant and non-regurgitant mitral valves (MV's) in patients with coronary artery disease and due to the heterogenous and regional nature of ischemic remodeling in patients with coronary artery disease (CAD), that the available anatomical reserve and likelihood of developing mitral regurgitation (MR) is variable in non-regurgitant MV's in patients with CAD.
Methods: In this retrospective, observational study intraoperative three-dimensional transesophageal echocardiographic data was analyzed in patients undergoing coronary revascularization with MR (IMR group) and without MR (NMR group). Regional geometric differences between both groups were assessed and MV reserve which was defined as the increase in antero-posterior (AP) annular diameter from baseline that would lead to coaptation failure was calculated in three zones of the MV from antero-lateral (zone 1), middle (zone 2), and posteromedial (zone 3).
Article Synopsis
- Transcatheter mitral valve replacement (TMVR) is a minimally invasive approach for treating mitral valve disease, facing challenges like various potential complications; supra-annular devices pose a lower risk since they anchor at the left atrial (LA) level.
- An experimental study was conducted on 10 male Dorsett sheep to explore LA systolic and diastolic geometry using MRI and echocardiography after inducing ischemic mitral regurgitation (IMR) through myocardial infarction (MI), with a follow-up at 8 weeks.
- Results showed that while there was significant IMR observed in surviving animals, key geometric parameters of the LA remained stable, providing insights for future development of TMVR devices that utilize LA
Conventional open harvesting of the radial artery as a conduit for coronary artery bypass grafting.
Multimed Man Cardiothorac Surg
August 2021
This video tutorial summarizes the main steps of the conventional open surgical technique for harvesting the radial artery as a coronary artery bypass graft, taking anatomic and surgical aspects into account.
View Article and Find Full Text PDFObjectives: Aortic valve endocarditis is occasionally complicated by periannular spreading of the infection and abscess formation, leading to a more aggressive course of the disease and life-threatening complications. This retrospective observational study investigated the long-term outcomes of patients with this complication, which was surgically managed with annular reconstruction and aortic valve replacement.
Methods: Between 1998 and 2018, 69 patients were identified with aortic valve endocarditis complicated by periannular abscess formation.