A deep learning framework deploying segment anything to detect pan-cancer mitotic figures from haematoxylin and eosin-stained slides.

Mitotic activity is an important feature for grading several cancer types. However, counting mitotic figures (cells in division) is a time-consuming and laborious task prone to inter-observer variation. Inaccurate recognition of MFs can lead to incorrect grading and hence potential suboptimal treatment.

Cognitive performance in ISS astronauts on 6-month low earth orbit missions.

Introduction: Current and future astronauts will endure prolonged exposure to spaceflight hazards and environmental stressors that could compromise cognitive functioning, yet cognitive performance in current missions to the International Space Station remains critically under-characterized. We systematically assessed cognitive performance across 10 cognitive domains in astronauts on 6-month missions to the ISS.

Methods: Twenty-five professional astronauts were administered the Cognition Battery as part of National Aeronautics and Space Administration (NASA) Human Research Program Standard Measures Cross-Cutting Project.

Quality and Success of Bone Graft from Two Different Mandibular Sites Compared for Maxillary Ridge Augmentation: A Systematic Review.

Aim: This systematic review was undertaken to compare the quality of autogenous bone graft harvested from two different mandibular donor sites, that is, from the chin region and from posterior mandibular region for maxillary alveolar ridge augmentation and success after implant placement.

Materials And Methods: Systematic searches were performed using PubMed, MEDLINE, and Cochrane electronic databases, which reported on the quality of autogenous harvested bone graft of the recipient site in maxillary alveolar ridge augmentation from a period of January 1995 to December 2020 using PRISMA guidelines. Studies were included if: They reported on bone grafts harvested from the chin and body region of the mandible.

Robotic cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: is there a benefit?

Background: Open cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is a therapeutic option for the management of malignancies with peritoneal carcinomatosis and of peritoneal origin. Robotic surgery shows promise as a minimally invasive approach for select patients. We aimed to evaluate the differences in outcomes between robotic versus open CRS/HIPEC and hypothesized less morbidity and faster recovery in the robotic approach group.

Evaluation of Implant Stability Quotient of Sandblasted Acid-Etched (SAE) and Chemical-Modified SAE Dental Implants: A Clinical Study.

Objectives: The goal of the current research was to assess the implant stability quotient (ISQ) of dental implants that were chemically changed with SAE and without SAE.

Materials And Methods: Patients in the current study had dental implants fitted with SAE (Group I) and chemically altered SAE (Group II). After implant implantation, resonance frequency analysis (RFA) was performed as soon as possible as well as one, three, six, nine, and twelve weeks later.