Budd-Chiari syndrome (BCS) is a rare disorder characterized by hepatic venous outflow obstruction, leading to substantial effects, which include liver congestion, ascites, and liver failure. This is an unusual but very important form of secondary BCS caused by extraluminal compression from structures such as abscesses, tumors, or cysts. This case study exemplifies a 46-year-old female with no previous medical history who developed BCS due to the encasement of the IVC and hepatic veins secondary to a hydatid cyst, which is an uncommon presentation.
View Article and Find Full Text PDFEarly diagnosis and ultrahigh sample throughput screening are the need of the hour to control the geological spread of the COVID-19 pandemic. Traditional laboratory tests such as enzyme-linked immunosorbent assay (ELISA), reverse transcription polymerase chain reaction (RT-PCR) and computed tomography are implemented for the detection of COVID-19. However, they are limited by the laborious sample collection and processing procedures, longer wait time for test results and skilled technicians to operate sophisticated facilities.
View Article and Find Full Text PDFBackground & Objectives: The Department of Health Research and the Indian Council of Medical Research, Government of India, have established Virus Research and Diagnostic Laboratory Network (VRDLN) to strengthen the laboratory capacity in the country for providing timely diagnosis of disease outbreaks. Fifty-one VRDLs were functional as on December 2017 and had reported about dengue fever across Indian states. The objectives of the study were to detect space time clusters and purely temporal clusters of dengue using Kulldorff's SaTScan statistics using patient level information; and to identify regions at greater risk of developing the disease using Kriging technique aggregating at district level.
View Article and Find Full Text PDFThis work addresses the synthetic optimization of carbon dots (CDs) and their application in sensing picric acid from latent fingerprints by exploiting a smartphone-based RGB tool. The optimization of the synthesis of CDs is investigated towards achieving shorter reaction time, better product yield and fluorescence quantum efficiency. Precursors such as citric acid and thiourea were chosen for the synthesis of CDs.
View Article and Find Full Text PDFDeveloping a fluorescent probe for the selective and sensitive detection of explosives is a topic of continuous research interest. Additionally, underlying the principles behind the detection mechanism is indeed providing substantial information about the design of an efficient fluorescence probe. In this context, a pyrene-tethered 1-(pyridin-2-yl)imidazo[1,5-]pyridine-based fluorescent probe (TL18) was developed and employed as a fluorescent chemosensor for nitro explosives.
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