Conversion of nested reverse-transcriptase polymerase chain reaction from positive to negative status at peripheral blood during androgen ablation therapy is associated with long progression-free survival in stage D2 prostate cancer patients.

Background: Nested reverse-transcriptase polymerase chain reaction (nested rt-PCR) for the detection of mRNA of prostate specific antigen (PSA) and prostate specific membrane antigen (PSMA) in peripheral blood samples (PB) and bone marrow biopsies (BM) can assess the extraprostatic growth of prostate cells.

Materials And Methods: Nested rt-PCR for PSA and PSMA at PB and BM was performed (a) at diagnosis, (b) after 6 months from the initiation of combined androgen blockade [(CAB); triptorelin 3.75 mg, i.

Abdomino-perineal repair of recurrent and complex bladder neck-prostatic urethra contractures.

Objective: To evaluate the effectiveness of abdomino-perineal repair in treating complex and recurrent bladder neck-prostatic urethra contractures.

Methods: The study included 6 patients retrospectively. Their ages ranged from 66 to 75 years (67.

Observations on 1,000 Millin prostatectomies.

1,000 Millin prostatectomies were performed under general anaesthesia and normal conditions of blood pressure (without hypotension) over a period of 6 years. Observations were made as to the blood losses (Davillas and Miliaressis, 1972), the length of hospitalization, the various complications and the death causes in 17 patients (1.7%).