[Prophylactic prescription of low-molecular-weight heparin in the non-surgical setting: impact of recommendations].

Objective: Low-molecular-weight heparins (LMWH) had official approval for use for venous thromboembolism prophylaxis only for surgery patients when this survey was conducted, but were nevertheless often used in non-surgery patients. We conducted this "before and after" survey from May 1998 to April 1999 to assess the impact of the recommendations implemented in the beginning of 1999.

Methods: Data on the use of LMWH were collected on three different days within a three week interval in all non-surgery departments at the Tenon hospital before distribution of expert recommendations early in 1999.

Cutaneous microvascular blood flow and reactivity in patients with homozygous sickle cell anaemia.

Homozygous sickle cell anaemia (SS disease) involves a high prevalence of skin ulcerations, and background experience concerning the cutaneous microcirculatory flux and reactivity in this disease is very limited. We investigated, by laser-Doppler velocimetry, the microcirculatory cutaneous blood flow and vasoreactivity in 17 patients with SS disease but no cutaneous trophic changes, vs. the corresponding values in 18 normal matched controls.

Long-term administration of high-dose deferoxamine 2 days per week in thalassemic patients.

Objective: Compliance with parenteral administration of deferoxamine is often poor in thalassemic patients with iron overload. We tested the efficacy and tolerance of the drug at high dosage 2 d per week for 24 months in two adult thalassemic patients with permanently high serum ferritin using a portable pump and an implanted chamber.

Methods: Deferoxamine was administered using a pressure-operated portable pump through an implanted chamber.

Statistical Evaluation of Algebraic Constraints for Social Networks.

A multirelational social network on a set of individuals may be represented as a collection of binary relations. Compound relations constructed from this collection represent various labeled paths linking individuals in the network. Since many models of interest for social networks can be formulated in terms of orderings among these labeled paths, we consider the problem of evaluating an hypothesized set of orderings, termed algebraic constraints.