Background: Chest pain is the second most common reason to present to the emergency department in the United States, and the ECG is a first-line diagnostic tool for myocardial ischemia assessment. For patients with ongoing symptoms or unclear initial ECGs, guidelines recommend performing multiple standard ECGs at 15-30-min intervals during the first 1-2 h, which improves acute coronary syndrome (ACS) detection by 15 % and accelerates triage of high-risk ACS patients. However, obtaining serial ECG is not consistently practiced due to overcrowding and the limited technical abilities of current 12‑lead ECG machines.
View Article and Find Full Text PDFThis study explored the use of amino acid-based ionic liquids to facilitate the conversion of carbon dioxide (CO) into methanol through catalytic hydrogenation. Combining tetrabutylammonium L-argininate (TBA⋅Arg) with the ruthenium Ru-MACHO-BH complex allowed achieving significant yields of methanol under optimized conditions, with a turnover number (TON) up to 700. By systematically varying key reaction parameters, we demonstrated that the TBA⋅Arg ionic liquid promotes the efficient hydrogenation pathway leading to methanol formation, thus offering a sustainable approach to CO valorization.
View Article and Find Full Text PDFMolybdenum(0) complexes with aliphatic aminophosphine pincer ligands have been prepared which are competent for the disproportionation of formic acid, thus representing the first example so far reported of non-noble metal species to catalytically promote such transformation. In general, formic acid disproportionation allows for an alternative access to methyl formate and methanol from renewable resources. MeOH selectivity up to 30% with a TON of 57 could be achieved while operating at atmospheric pressure.
View Article and Find Full Text PDFWhile Europe's response to the pandemic has been laudable, there remains more to be done in order to prevent economic scarring and ensure a robust recovery.
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