Publications by authors named "A Kambal"
Article Synopsis
- RSV is more severe in infants than in adults, but the reasons for this difference are not fully understood.
- Researchers used nasal organoid models from both infants and adults to explore how their nasal linings respond to RSV infection.
- The study found that infant nasal cells had a stronger viral response, more mucus production, and greater cell damage, suggesting that infants’ immune responses might lead to more severe infections than in adults.
Article Synopsis
- Nasal colonization by certain bacteria increases infection risk, while others are linked to health; this study used human nasal epithelial organoids (HNOs) to explore these dynamics.
- HNOs were successfully colonized with three bacterial species for up to 48 hours, showing minimal harm and allowing for the bacteria to localize in the mucus.
- The research identified specific immune responses to the bacterial species, indicating that some bacteria trigger inflammation while others modulate immune signaling without causing infection.
Objectives: The objective of this study was to compare short-term outcomes of pancreatoduodenectomy between patients with and without liver cirrhosis (LC).
Background: It is not uncommon to encounter a patient with LC and with an indication for pancreatoduodenectomy; however, the knowledge on the outcomes after pancreatoduodenectomy in patients with LC is poorly developed.
Methods: A systematic review and meta-analysis was conducted in line with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement standards.
Cystic artery stump pseudoaneurysm (CASP) is a potentially life-threatening condition that can be related to multiple etiologies, especially the iatrogenic factor owing to the increased number of hepatobiliary procedures. Most patients present with haemobilia. Here we report a successfully managed case of CASP that initially complained of right upper abdominal pain.
View Article and Find Full Text PDFUnlabelled: Human intestinal enteroids (HIEs) are gaining recognition as physiologically relevant models of the intestinal epithelium. While HIEs from adults are used extensively in biomedical research, few studies have used HIEs from infants. Considering the dramatic developmental changes that occur during infancy, it is important to establish models that represent infant intestinal characteristics and physiological responses.
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