Publications by authors named "A KAWADA"
Diabetes mellitus increases oxidative stress due to hyperglycemia, resulting in the degeneration of rotator cuff tissue. Currently, there is no established method to non-invasively assess the extent of this oxidative stress. To address this, we aimed to investigate the relationship between the accumulation of advanced glycation end-products (AGEs), a marker of oxidative stress, and transcutaneous autofluorescence intensity in rotator cuff tissue harvested from diabetic rats.
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- A systematic review examined the impact of interdisciplinary home healthcare services, involving at least two providers (like nurses and physiotherapists), on the quality of life and health outcomes in older adults with chronic conditions.
- The review included 13 randomized controlled trials (RCTs) with 4,709 participants, finding that these services significantly reduced hospital admissions in the first 6 months of care, though certainty around quality of life and mortality outcomes was low.
- The study concluded that while interdisciplinary home care may lower hospital admissions, more thorough research is needed to assess its overall effectiveness on other health outcomes.
Objective: Telenursing e-learning courses have been shown to enhance nurses' skills and knowledge; however, the subjective learning experience is unclear. In this study, we identified meta-inferences to quantitatively and qualitatively understand this experience, as well as the types of knowledge gained through an e-learning course and how they are linked to each other, in order to enhance nurses' confidence in their understanding of telenursing.
Methods: We employed a single-arm intervention with a mixed-methods convergent parallel design.
Article Synopsis
- CCR4 is identified as an important receptor for T-helper 2 (Th2) and Th17 cells and is a potential target for treating atopic dermatitis (AD).
- In a mouse model of AD induced by MC903 (a TSLP inducer), increased levels of Th2 and Th17-related cytokines and immune cell infiltration were observed, leading to skin lesions.
- Using a CCR4 inhibitor, Compound 22, showed promise in reducing Th2 and Th17 cells and improving AD-like symptoms, suggesting CCR4 antagonists could help manage allergic reactions in AD.
Purpose: To retrospectively review locally advanced cervical cancer (CC) cases treated with three-dimensional image-guided brachytherapy (3D-IGBT) and two-dimensional (2D)-IGBT.
Materials And Methods: Patients with Stage IB-IVa CC who underwent intracavitary irradiation between 2007 and 2021 were divided into the 3D-IGBT and 2D-IGBT groups. Local control (LC), distant metastasis-free survival (DMFS), progression-free survival (PFS), overall survival (OS), and gastrointestinal toxicity (G3 or more) were investigated at 2/3 years post-treatment.