Publications by authors named "A K Winkler"

Background: Neurocysticercosis (NCC) and Acquired Human Immunodeficiency Syndrome (AIDS) are both highly prevalent in Africa. Clinical presentation of NCC ranges from asymptomatic to manifestations, including epileptic seizures, severe progressive headache, and focal neurological deficits. It is influenced by the number, size, location, and stage of the cysts, as well as the parasite's potential to cause inflammation and the immunological response of the host.

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Introduction: Epilepsy is one of the most common neurological conditions worldwide, with large variation in prevalence across Sub-Saharan Africa countries. Northern Uganda is one of the poorest areas of the country and has seen high density of pigs and prevalence of Taenia solium, a zoonotic tapeworm transmitted which cause neurocysticercosis in humans. The objective of this study was to estimate the population-level prevalence of active epilepsy in 25 sub-counties of northern Uganda.

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Individual differences in how the brain responds to novelty are present from infancy. A common method of studying novelty processing is through event-related potentials (ERPs). While ERPs possess millisecond precision, spatial resolution remains poor, especially in infancy.

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Article Synopsis
  • The study examines how brain connectivity, both structural and functional, influences the development of mental health issues in adolescents.
  • The research uses advanced MRI techniques to compare brain structure and activity, focusing on a group of youth with high symptom levels.
  • Results suggest that stronger connections between certain brain networks are linked to increased negative emotions, which might hinder important brain changes needed for positive mental health outcomes during adolescence.
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The saddle nose deformity is associated with dorsal collapse and can have both function and cosmetic problems. The saddle nose can cause nasal obstruction by narrowing the nasal cavities, eliciting dynamic internal and external nasal valve narrowing, and abnormally widening the internal and external nasal valves altering airflow dynamics, sinonasal passageways, and olfaction. The saddle nose is challenging to treat due to skin contracture, lack of donor tissue, and difficulties in esthetic integration.

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