Background: Fibrous dysplasia (FD) is often difficult for skull base surgeons to address. FD arises due to the abnormal proliferation of fibroblasts, ultimately resulting in immature osseous tissue replacing normal cancellous bone. When the skull base is involved, it can result in cranial nerve compression.
View Article and Find Full Text PDFBackground: Orthopaedic sports medicine is among the most popular subspecialties. Understanding the trends in sports medicine research over time can offer insight into progress and innovation within the field. The purpose of this study was to assess both the quality of the current literature and trends in gender diversity and inclusion by evaluating publishing characteristics of sports medicine studies in The from 2007 to 2021.
View Article and Find Full Text PDFDue to advancements in medical care and reconstructive surgery, more patients with bladder exstrophy are reaching reproductive age and considering pregnancy. Complications are more common during pregnancy in this patient population, given medical comorbidities and prior surgical intervention. In the case of cesarean delivery, careful planning is necessary to prevent inadvertent injury to the bladder or bowel segments.
View Article and Find Full Text PDFFor investigations into fate specification and morphogenesis in time-lapse images of preimplantation embryos, automated 3D instance segmentation and tracking of nuclei are invaluable. Low signal-to-noise ratio, high voxel anisotropy, high nuclear density, and variable nuclear shapes can limit the performance of segmentation methods, while tracking is complicated by cell divisions, low frame rates, and sample movements. Supervised machine learning approaches can radically improve segmentation accuracy and enable easier tracking, but they often require large amounts of annotated 3D data.
View Article and Find Full Text PDF