Clinical significance of acetylcholinesterase activity in brain tumors.

It has been established that the non-neuronal cholinergic system is related to the oncogenesis which increases the attractiveness of its components as the promising markers of oncologic diseases. The purpose of this work is to evaluate the clinical significance of the analysis of the activity of acetyl cholinesterase as a new marker of gliomas. The activity of acetyl cholinesterase was assessed by photo colorimetric analysis according to the Hestrin method recalculating the activity of the enzyme in the tumor tissue per 1 g of protein, and in the blood - by 0.

Pulmonary Tuberculosis: Decreased Activation of T lymphocyte Subsets in vitro.

Protection against M. tuberculosis depends on T cells of the CD4(+) or CD8(+) phenotype. The definition of cellular response and target molecules are important to understand pathological immune mechanisms in tuberculosis.

[Phenotype of peripheral blood lymphocytes of healthy donors and patients with corneal allotransplantation under conditions of hyperbaric oxygenation].

The purpose of this study was to elucidate the possible immunomodulating effect of hyperbaric oxygenation (HBO) on the immune status of patients with various ophthalmopathies and developing the graft-versus-host reaction after perforating keratoplasty. Surface phenotype of the peripheral blood lymphocytes was studied by two-color flow cytofluorometry in donors and patients with the rejection syndrome after transplantation of the cornea before and after a course of oxygen therapy. HBO exerted no immunodepressive effect, as judged from changes in the subpopulation composition (CD3+, CD4+, CD8+, CD16+, and CD56+) and expression of activation markers (CD25 and HLA-DR), in both patients and donors.