Publications by authors named "A K Veenendaal"
Continuous vital sign monitoring (CM) may detect ward patient's deterioration earlier than periodic monitoring. This could result in timely ICU transfers or in a transfer delay due to misperceived higher level of care on the ward. The primary objective of this study was to compare patient's disease severity upon unplanned ICU transfer, before and after CM implementation.
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- The global medical workforce, despite appearing unified with various specialties, reveals significant differences in training and regulations among countries.
- Recent efforts, particularly in Germany, the USA, Canada, the UK, Australia, and the Netherlands, focus on standardizing postgraduate specialty training through competency frameworks, though clear objectives remain a challenge.
- The introduction of milestones for trainee progress and the concept of entrustable professional activities show promise for improving training consistency, but it remains uncertain if true harmonization will be achieved globally.
Salicylidene acylhydrazides identified as inhibitors of virulence-mediating type III secretion systems (T3SSs) potentially target their inner membrane export apparatus. They also lead to inhibition of flagellar T3SS-mediated swimming motility in Salmonella enterica serovar. Typhimurium.
View Article and Find Full Text PDFBackground: Natural compounds with anti-microbial properties are attractive reagents to reduce the use of conventional antibiotics. Carvacrol, the main constituent of oregano oil, inhibits the growth of a variety of bacterial foodborne pathogens. As concentrations of carvacrol may vary in vivo or when used in animal feed, we here investigated the effect of subinhibitory concentrations of the compound on major virulence traits of the principal bacterial foodborne pathogen Campylobacter jejuni.
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- The European ban on antibiotic growth promoters has led to the exploration of alternatives like essential oils for improving pig health and growth.
- Carvacrol, an essential oil component, was found to completely inhibit the motility of Salmonella Typhimurium without affecting its growth.
- While carvacrol did not impact the adhesion of Salmonella to intestinal cells, it significantly reduced the bacteria's ability to invade and decreased the expression of porcine β-defensin 2, indicating this immune response is triggered primarily by bacterial invasion.