Publications by authors named "A K Uduman"
Article Synopsis
- Reliable maps of species distributions, like the IUCN range maps, are crucial for biodiversity research but often don't match actual occurrence data.
- A study found that camera traps detected only 39% of expected species based on IUCN and recent area of habitat (AOH) maps, with most mismatches occurring near range edges.
- The findings highlight that while range maps may not miss areas where species exist, they often include areas where species are absent, stressing the need to combine maps with ground-based data for better conservation planning.
Clinical studies have shown that cigarette smoking is a dose-dependent and independent risk factor for acute pancreatitis. Cigarette smoke contains nicotine which can be converted to the potent receptor ligand and toxin, NNK [4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone]. Previously, we have shown that NNK induces premature activation of pancreatic zymogens in rats, an initiating event in pancreatitis, and this activation is prevented by pharmacologic inhibition of nicotinic acetylcholine receptors (nAChR).
View Article and Find Full Text PDFTobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone initiates and enhances pancreatitis responses.
Am J Physiol Gastrointest Liver Physiol
September 2012
Clinical studies indicate that cigarette smoking increases the risk for developing acute pancreatitis. The nicotine metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is a major cigarette smoke toxin. We hypothesized that NNK could sensitize to pancreatitis and examined its effects in isolated rat pancreatic acini and in vivo.
View Article and Find Full Text PDF