Publications by authors named "A K Swidnicka-Siergiejko"

Acute pancreatitis (AP) is one of the most common diseases of the gastrointestinal tract, which in 20% of cases can turn into a severe form, with mortality reaching up to 30%. One of the cornerstones of AP treatment is early nutritional treatment. Feeding intolerance (FI) occurs in up to 25% of patients with AP and is associated with a more severe disease course and poorer clinical outcome.

View Article and Find Full Text PDF

Background/aims: Intestinal metaplasia (IM) of the stomach is a precancerous condition that is often not visible during conventional endoscopy. Hence, we evaluated the utility of magnification endoscopy and methylene blue (MB) chromoendoscopy to detect IM.

Methods: We estimated the percentage of gastric mucosa surface staining with MB, mucosal pit pattern, and vessel visibility and correlated it with the presence of IM and the percentage of metaplastic cells in histology, similar to the Operative Link on Gastric Intestinal Metaplasia (OLGIM) stage.

View Article and Find Full Text PDF

BACKGROUND The COVID-19 pandemic affected many people worldwide, including those with chronic diseases. Our objective was to analyze its influence on medical care and the course of inflammatory bowel disease (IBD) in Poland. MATERIAL AND METHODS In 2021, 81 patients in Poland with IBD completed an original anonymous questionnaire about the impact of the COVID-19 pandemic on the course of their disease and mental status.

View Article and Find Full Text PDF
Article Synopsis
  • Epidemiological studies link cigarette smoking with chronic pancreatitis (CP), and this research aims to explore whether cigarette smoking increases K-Ras expression and contributes to CP development in mice.
  • Mice were exposed to cigarette smoke and underwent repeated treatments to simulate acute pancreatitis, with their pancreatic damage assessed through various histological techniques.
  • Findings show that while CS and cerulein alone did not cause chronic damage, their combination led to mild CP symptoms and increased expression of K-Ras and NF-κB in the pancreas.
View Article and Find Full Text PDF

Purpose: Due to the lack of systematic data on antibiotic sensitivity, the treatment of the highly prevalent and pathogenic () infection still poses a significant problem. Therefore, the aim of our study was to compare the efficacy of the three most commonly used anti- therapies in northeastern Poland.

Patients And Methods: This was a retrospective, single-center study performed on 289 outpatients with an infection.

View Article and Find Full Text PDF