[Clinical aspects of a virtual operating room for the prediction of operative interventions in some disease of the middle ear].

Clinical aspects of creating a software system for simulation and prediction of operative interventions and hearing function changes are considered. The system will make simulation and prediction transparent and convenient for the user. The technical challenge is to create mediation languages which enforce rigorous mathematical computation while supporting intuitive behaviour.

An approach for access differentiation design in medical distributed applications built on databases.

A formalized "top to bottom" design approach was described in [1] for distributed applications built on databases, which were considered as a medium between virtual and real user environments for a specific medical application. Merging different components within a unified distributed application posits new essential problems for software. Particularly protection tools, which are sufficient separately, become deficient during the integration due to specific additional links and relationships not considered formerly.

[Immunological features of patients with polypous ethmoiditis].

34 patients with nasal polyps (NP) and 12 normal individuals were studied immunologically to investigate association of nasal polyp formation with disorders of general and local immunity. In NP patients there were decreased preoperative and early postoperative levels of peripheral blood T- and B-lymphocytes, functional activity of lymphocytes and neutrophils. In contrast to normal individuals, nasal secretion of NP patients contained degenerative epithelial cells and neutrophils, activated lymphocytes, monocytes and eosinophils.