Publications by authors named "A K Sah"
Article Synopsis
- The study focused on analyzing multidrug-resistant (MDR) isolates for their ability to form biofilms and the presence of associated genes at a hospital in Nepal.
- A significant majority of the isolates were found to be strong biofilm producers, with 195 out of 200 being MDR and 192 capable of biofilm formation.
- Cinnamaldehyde was the most effective compound in inhibiting biofilm formation, with essential oils and Tween 80 also showing high efficacy, providing insights for potential treatment options against these resistant strains.
Can quantitative perfusion CT-based biomarkers predict renal cell carcinoma subtypes?
Abdom Radiol (NY)
December 2024
Purpose: To assess diagnostic accuracy of perfusion CT (pCT) based biomarkers in differentiating clear-cell renal cell carcinoma (ccRCC) from non-ccRCC.
Materials And Method: This retrospective study comprised 95 patients with RCCs (70 ccRCCs and 25 non-ccRCCs) who had perfusion CT (pCT) before surgery between January 2017 and December 2022. Two readers independently recorded PCT parameters [blood flow (BF), blood volume (BV), mean transit time (MTT), and time to peak (TTP)] by drawing a circular ROI on the tumor.
Article Synopsis
- A dinuclear molybdenum complex combined with urea hydrogen peroxide has been developed as an effective catalyst for converting thiols into uronium sulfonate salts with high yields (89-98%) in ethanol at room temperature.
- The reaction produced hydrogen gas, a pioneering finding in similar oxidation processes, and detailed product characterization was conducted using techniques like FTIR, NMR, and single crystal X-ray diffraction.
- Mechanistic studies revealed intermediate products including disulfides and sulfinic acids, while two specific reactions illustrated the conversion of uronium p-chlorobenzene sulfonate to sulfonic acid and diphenyl diselenide to selenonate salt.
Precipitate, preterm labor in acute organophosphate poisoning in pregnancy: a case report.
Ann Med Surg (Lond)
December 2024
Introduction: Acute organophosphorus poisoning (AOPP) during pregnancy is uncommon. When complicated by preterm labor, it presents therapeutic dilemmas due to the lack of established guidelines.
Case Presentation: The authors describe a case of a 19-year-old primigravida at 33 weeks of gestation with AOPP.
Introduction And Objectives: Metabolic dysfunction-associated steatotic liver disease (MASLD) is one of the primary causes of chronic liver disease and may lead to liver cirrhosis and hepatocellular carcinoma. Recent reports suggested that DEAD-box RNA helicase (DDX3) acts as a sensor of free fat accumulation and may modulate the pathogenesis via miRNAs. Hence, we hypothesized that DDX3 might modulate MASLD progression via miRNA-141-mediated inhibition of Sirt-1 and autophagy.
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