Publications by authors named "A K Radhakrishnan"
Cholesterol is a critical lipid that is present at high concentrations in the plasma membranes of animal cells. Most of the membrane cholesterol is sequestered by other membrane lipids and the transmembrane domains of proteins. Cholesterol in excess of such sequestration forms a pool that is referred to as "accessible cholesterol.
View Article and Find Full Text PDFPurpose: Very little is known about primary care involvement in the care of cancer survivors beyond the initial 5 years post-treatment when transitioning to primary care is guideline-recommended for many survivors.
Methods: The ICanCare study is a longitudinal survey of women diagnosed with breast cancer in 2014-2015 identified in the Georgia and Los Angeles SEER registries. Women were surveyed during initial treatment and again approximately 6 years later in survivorship (2021-2022; n = 1,412, 60% response rate).
Article Synopsis
- The audit aimed to assess and improve the completeness and accuracy of the National Joint Registry (NJR) dataset specifically for elbow arthroplasty surgeries.
- In a two-phase approach, Phase 1 compared NJR data with NHS England Hospital Episode Statistics (HES), identifying thousands of unmatched and inaccurate records, particularly for radial head arthroplasties (RHAs).
- Phase 2 involved collaboration among 142 NHS hospitals to correct and update records, resulting in an improved completeness of the NJR dataset from 63% to 93% and accuracy from 94% to 98%.
Purpose: The occurrence of new seizure(s) in older adults is two- to three-fold higher as compared to the younger population, and previous studies have characterized the clinical features of seizures in patients beyond 60 or 65 years. This study, in response to the recent ILAE task force on epilepsy in the elderly (2023), has assessed the clinical characteristics of individuals who are over 85 years old.
Methods: Data was collected from prospectively maintained electronic medical records, and the participants were divided into seizure-free and seizure-recurrence groups, and their clinical characteristics were compared.
Article Synopsis
- A study was conducted on spotted seals in Peter the Great Bay to measure the levels of halogenated organic pollutants (HOPs), revealing high accumulation of polychlorinated biphenyls (PCBs) and organochlorine pesticides despite regulations.
- *The research found that older seals had higher levels of hexabromocyclododecanes, and identified 35 additional non-target PCBs that are not regularly monitored, indicating a gap in current assessment methods.
- *Alarmingly, 95% of the seals had PCB levels surpassing safe thresholds, showing the urgent need for more comprehensive monitoring strategies to evaluate the health risks of HOPs to marine life.