Publications by authors named "A K Praharaj"
Introduction: The rising incidence of carbapenem resistance in Enterobacterales and is a concern. Since carbapenemase production is the primary resistance mechanism, detecting and identifying the genes responsible for it is crucial to effectively monitor its spread.
Objective: This study aims to detect positivity for the modified carbapenem inactivation method (mCIM) and ethylenediaminetetraacetic acid (EDTA)-carbapenem inactivation method (eCIM) for the detection of carbapenemase-producing Enterobacterales and .
This study has been designed to analyse the academic landscape of AI on the Scopus and Web of Science (WOS) indices and compare the findings. AI is one of the most prominent and preferred research areas, only a few studies are dedicated to the bibliometric aspect of it. There is a need to compare studies on AI over different databases to identify the impact and usefulness of those studies in decision-making in business management.
View Article and Find Full Text PDFMethicillin-resistant (MRSA) is one of the major causes of hospital and community-acquired infections. Fewer drugs, such as vancomycin, teicoplanin, and daptomycin, are effective against it, but they come with high toxicity. Fifth-generation cephalosporins like ceftaroline and second-generation cefuroxime are effective against MRSA.
View Article and Find Full Text PDFBackground Patients with chronic kidney disease and undergoing hemodialysis are at greater risk of developing COVID-19. In spite of vaccine efficacy, SARS-CoV-2 breakthrough infection has been reported in several studies. This study was carried out to assess if seroconversion could predict SARS-CoV-2 breakthrough infection in a cohort of vaccinated patients undergoing hemodialysis.
View Article and Find Full Text PDFArticle Synopsis
- Colistin is the last treatment option for infections from multi-drug resistant gram-negative bacteria, but recently there has been a rise in resistance to this drug, particularly in clinical settings.
- A study carried out in an ICU in Eastern Odisha, India, from March 2019 to February 2020, found that 19.6% of the MDR gram-negative isolates were resistant to colistin, with high occurrences in respiratory infections and neurology patients.
- The majority of patients (74.2%) recovered, and interestingly, a significant number of ICU patients (57.9%) had no co-morbidities, indicating that colistin resistance is an emerging concern in managing infections in the ICU.