Publications by authors named "A K Pesonen"
The natural world is under unprecedented and accelerating pressure. Much work on understanding resilience to local and global environmental change has, so far, focussed on ecosystems. However, understanding a system's behaviour requires knowledge of its component parts and their interactions.
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- Sleep plays a significant role in regulating emotions, but its specific contributions, particularly concerning physiological responses to stress, are not well understood.
- A study involving Finnish participants explored the effects of suppressing specific sleep stages (REM and slow-wave sleep) on stress responses and memory, finding that suppressing slow-wave sleep resulted in a greater physiological stress response.
- The research suggests that REM sleep, specifically its theta brain activity, helps consolidate emotional responses, while the dependence of declarative memory consolidation on sleep stages is less clear.
Article Synopsis
- Evidence suggests that rapid-eye-movement sleep (REMS) plays a critical role in processing emotions, with systematic reviews focusing on the effects of REMS deprivation (REMSD).
- Animal studies show that longer REMSD leads to negative outcomes such as aggression, increased pain sensitivity, diminished sexual behavior, and impaired fear memory consolidation, while human studies mostly report effects after just one night of deprivation.
- There is a significant lack of research on the effects of chronic REMS suppression, especially considering the potential impact of medications like SSRIs, highlighting a gap in understanding its long-term consequences on emotional health.
Objectives: Evidence of the impact of chronic stress on sleep is abundant, yet experimental sleep studies with a focus on acute stress are scarce and the results are mixed. Our study aimed to fill this gap by experimentally investigating the effects of pre-sleep social stress on sleep dynamics during the subsequent night, as measured with polysomnography (PSG).
Methods: Thirty-four healthy individuals (65% females, M = 25.
Aims: Both effective analgesia and early breastfeeding play an important role in maternal and neonatal well-being after Caesarean delivery. We studied controlled-release oxycodone tablet treatment for postoperative pain management and determined the excretion of oxycodone into breast milk.
Methods: Controlled-release oxycodone/naloxone 10/5-mg tablets (n = 21) or controlled-release oxycodone 10-mg tablets (n = 22) were administered to mothers twice a day for the first 3 days after elective Caesarean delivery as a part of multimodal analgesia.