Publications by authors named "A K Knight"

Background: There are currently 2.5 million people economically inactive in the UK due to sickness. The government is considering a range of new initiatives to bring them back into the workforce; however, a lack of occupational health (OH) professionals, who play an important part in the recovery of physical and mental conditions that would otherwise inhibit employees from working, is hindering these efforts.

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Outer membrane vesicles (OMVs) are small membrane enclosed sacs released from bacteria which serve as carriers of biomolecules that shape interactions with the surrounding environment. The periodontal pathogen, , is a prolific OMV producer. Here, we investigated how the structure of lipid A, a core outer membrane molecule, influences OMV production, OMV-dependent TLR4 activation, and biofilm formation.

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Article Synopsis
  • Primary ovarian insufficiency (POI) is when ovarian function stops before age 40, with notable genetic contributions, particularly from the X chromosome.
  • Recent research has identified both known and novel genes linked to POI, revealing that multiple genetic variants can be associated with the condition.
  • Current genetic testing for POI is limited, focusing mainly on the FMR1 gene, suggesting that broader testing could enhance diagnosis and treatment options for those affected.
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Introduction: Attention-deficit/hyperactivity disorder (ADHD) is common among Veterans but overlapping symptoms with other prevalent psychiatric disorders (e.g., posttraumatic stress disorder [PTSD]) complicate diagnosis.

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The synthetic toolbox for stimuli-responsive polymers has broadened to include many tunable variables, making these materials applicable in diverse technologies. However, unraveling the key composition-structure-function relationships to facilitate ground-up design remains a challenge due to the inherent dispersity in sequence and conformations for synthetic polymers. We here present a systematic study of these relationships using a model system of copolymers with a thermoresponsive (-isopropylacrylamide) backbone in addition to metal-chelating (acrylic acid) and hydrophobic structural comonomers and evaluate their efficiency at isolating technologically critical lanthanide ions.

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