Publications by authors named "A K Henders"
Article Synopsis
- - An estimated 65 million people globally experience post-acute sequelae of COVID-19 (PASC), with many suffering from specific cardiovascular symptoms (PASC-CVS) like chest pain and heart palpitations.
- - The study focuses on chronic inflammation in PASC-CVS patients, particularly those with symptoms lasting over a year, and shows a distinct blood signature indicating inflammation linked to their condition.
- - Findings reveal trace levels of pro-inflammatory cytokines and elevated complement and coagulation proteins in the blood of PASC-CVS patients, suggesting that chronic inflammation significantly impacts heart function in these individuals.
Cell-free DNA (cfDNA) is increasingly recognized as a promising biomarker candidate for disease monitoring. However, its utility in neurodegenerative diseases, like amyotrophic lateral sclerosis (ALS), remains underexplored. Existing biomarker discovery approaches are tailored to a specific disease context or are too expensive to be clinically practical.
View Article and Find Full Text PDFAutism omics research has historically been reductionist and diagnosis centric, with little attention paid to common co-occurring conditions (for example, sleep and feeding disorders) and the complex interplay between molecular profiles and neurodevelopment, genetics, environmental factors and health. Here we explored the plasma lipidome (783 lipid species) in 765 children (485 diagnosed with autism spectrum disorder (ASD)) within the Australian Autism Biobank. We identified lipids associated with ASD diagnosis (n = 8), sleep disturbances (n = 20) and cognitive function (n = 8) and found that long-chain polyunsaturated fatty acids may causally contribute to sleep disturbances mediated by the FADS gene cluster.
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