Development of Biofidelic Skin Simulants Based on Fresh Cadaveric Skin Tests.

The development of artificial skin that accurately mimics the mechanical properties of human skin is crucial for a wide range of applications, including surgical training for burn injuries, biomechanical testing, and research in sports injuries and ballistics. While traditional materials like gelatin, polydimethylsiloxane (PDMS), and animal skins (such as porcine and bovine skins) have been used for these purposes, they have inherent limitations in replicating the intricate properties of human skin. In this work, we conducted uniaxial tensile tests on freshly obtained cadaveric skin to analyze its mechanical properties under various loading conditions.

Frictional Performance of Geometrically Modified Footwear Outsoles with Obliquely Oriented Tread Patterns.

OCCUPATIONAL APPLICATIONSWe systematically examined the effect of obliquely-oriented shoe tread channels on traction performance, by manipulating tread angle, thickness, and gap width across 24 outsole designs. Through robotic slipping tribotesting and computational fluid dynamics modeling, outsoles with a tread inclination angle of 75 and 105 degrees, 2 mm tread thickness, and 5 mm gap width exhibited superior dry and wet traction. This work introduces experimental and computational techniques, offering potential for footwear manufacturers and those who prefer formal shoes to understand the effect of designs on the slip-resistance of a footwear for better safety.

Ultrafast ppb-Level Detection of Nitro-Furan Based Antibiotics in Aqueous Medium by an Oxadiazole-Grafted Luminescent Sensor.

This work is primarily focused on the utilization of an oxadiazole grafted 2D luminescent metal-organic framework, {[Zn(4-tpom)(oxdz)]⋅4HO} (1), in the detection of trace amounts of nitrofuran-based antibiotics such as nitrofurantoin (NFT) and nitrofurazone (NFZ) in aqueous medium. The π-electron rich moieties and the H-bond accepting sites in the dual linkers (4-tpom and oxdz) enable the framework to interact efficiently with NFT and NFZ exhibiting a turn-off fluorescence response with the respective K (6.55×10 M and 4×10 M) and LOD (89 ppb and 78 ppb) values.