Publications by authors named "A K Bayazıt"
Article Synopsis
- The study examines how various clinical, laboratory, and personal factors influence the choice and timing of kidney replacement therapy (KRT) among pediatric patients with chronic kidney disease (CKD).
- Researchers analyzed a cohort of 695 children aged 6 to 17 to identify what factors lead to either starting dialysis or receiving preemptive transplantation.
- Key findings show that kidney function decline, disease type, and other health indicators like blood pressure and hemoglobin levels significantly affect KRT decisions, with notable variations between different medical centers.
Background: Despite significant cardiovascular (CV) morbidity in children on dialysis and after kidney transplantation, data on the evolution of CV damage in children with chronic kidney disease (CKD) approaching kidney replacement therapy (KRT) is unknown.
Methods: The burden, progression, and predictors of CV damage before KRT onset were explored in two prospective multicenter cohorts from Europe and Canada: Cardiovascular Comorbidity in Children with CKD (4C) and Haemodiafiltration, Heart and Height (3H) studies, conducted from 2009-19 and 2013-16, respectively. CV damage and risk factors were evaluated (i) cross sectionally at KRT-start (n = 248), and (ii) longitudinally over the 2-years preceding KRT start (n = 157; 331 patient-visits).
Background: Continuous kidney replacement therapy (CKRT) has recently become the preferred kidney replacement modality for children with acute kidney injury (AKI). We hypothesise that CKRT technical parameters and treatment settings in addition to the clinical characteristics of patients may influence the circuit lifetime in children.
Methods: The study involved children included in the EurAKId registry (NCT02960867), who underwent CKRT treatment.
Introduction: Unlike idiopathic nephrotic syndrome (NS), hereditary podocytopathies are not expected to recur after kidney transplantation. However, some reports of posttransplant recurrence of NS in patients carrying variants in the gene have been described, notably with the p.Arg138Gln variant, which is more prevalent in Europe.
View Article and Find Full Text PDFBackground: Dyslipidemia is an important and modifiable risk factor for CVD in children with CKD.
Methods: In a cross-sectional study of baseline serum lipid levels in a large prospective cohort study of children with stage 3-5 (predialysis) CKD, frequencies of abnormal lipid levels and types of dyslipidemia were analyzed in the entire cohort and in subpopulations defined by fasting status or by the presence of nephrotic range proteinuria. Associated clinical and laboratory characteristics were determined by multivariable linear regression analysis.