Publications by authors named "A K Balapure"

Oral squamous cell carcinoma (OSCC) is the most common type of head and neck cancers. OSCC constitutes 90% of the head and neck malignancies. The delayed identification of oral cancer is the primary cause of ineffective medical treatment.

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Identification and evaluation of defect levels in low-dimensional materials is an important aspect in quantum science. In this article, we report a facile synthesis method of low-dimensional hexagonal boron nitride (h-BN) and study light emission characteristics due to the defects. The thermal annealing procedure is optimized to obtain clean multilayered h-BN as revealed by transmission electron microscopy.

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Caffeic acid (CA) is a naturally occurring plant-derived polyphenol possessing diverse biological properties. However, the poor water-solubility of CA restricts its widespread applications. On the other hand, biogenic amines such as spermine and spermidine are natural constituents in eukaryotes.

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Because of the broad-spectrum antimicrobial efficacy, silver-based coatings have emerged as the popular choice to apply over frequently touched surfaces for mitigating the spread of nosocomial infections. Despite the advancements through various coating strategies, clustering of the active component remains a bottleneck in achieving the molecular-scale dispersion of silver. To circumvent this, the current study takes advantage of the recent findings of quaternary ammonium moieties forming molecular complexes with silver salts that differ from the simple adduct between the individual components.

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Article Synopsis
  • Caffeic acid (CA) has limited applications due to its poor water solubility, but a new method using dopamine hydrochloride (Dopa.HCl) allows for the formation of a water-soluble complex without covalent bonds.
  • The solubility is achieved after using sodium bicarbonate to neutralize the mineral acid in the mixture, resulting in a water-soluble CA-Dopa complex.
  • This complex has been shown to have strong bactericidal, antibiofilm, antioxidant, and anticancer properties in a pH range relevant to physiological conditions (5.5 to 7.5), highlighting its potential for various applications.
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