Publications by authors named "A Juzgado"

Prostate-specific membrane antigen (PSMA), a glycoprotein expressed in the prostatic epithelium endowed with enzymatic activity, is a very promising diagnostic marker for the early detection of prostate cancer. In this study, we report a novel electrochemiluminescence ELISA-like immunosensor based on carbon nanotubes and a highly specific sandwich immunoassay for the PSMA detection. To fabricate the device, an optically transparent electrode was modified with doubly functionalized multi-walled carbon nanotubes carrying amine groups and a monoclonal anti-PSMA antibody.

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Article Synopsis
  • A C(4)-bound palladium-N-heterocyclic carbene was derived from a C(2)-unsubstituted imidazolium salt.
  • The stability of the C(4) attachment is enhanced by chelation from pyridine, which helps stabilize the complex.
  • This process enabled the successful formation of a mesoionic compound.
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Unlabelled: The common diagnostic methods to know primary hemostasis have been classified as invasive, depending on the operator, difficult to reproduce and at times not very reliable. Thus, different systems have been proposed to assess bleeding time, one of them being the PFA-100 device, which we present in this paper.

Objective: Compare specificity between the traditional Ivy method with the PFA-100 system to measure bleeding time.

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