Rabies incidence and burden in three cities of Cameroon (2004-2013).

Rabies is a fatal disease occurring worldwide and especially in almost all the countries in Asia and Africa including Cameroon. Though animal and human rabies is prevalent in Cameroon, the epidemiology and socio-economic burden of the disease in the country is not known. Therefore, a 10-year (October 2004-April 2013) retrospective study on the incidence of animal and human rabies and its burden in Garoua, Ngaoundéré and Yaoundé in Cameroon was carried out.

Robustness of Optimal Circadian Rhythm Entrainment under Model Perturbation.

The optimal circadian rhythm entrainment problem has been studied based on mathematical models, e.g. the Kronauer model.

Efficient Estimation of the Human Circadian Phase via Kalman Filtering.

Circadian rhythms play a vital role in maintaining a person's well-being but remain difficult to quantify accurately. Numerous approaches exist to measure these rhythms, but they often suffer from performance issues on the individual level. This work implements a Steady-State Kalman Filter as a method for estimating the circadian phase shifts from biometric signals.

, a new species of Primulaceae (Myrsinoideae) from Peninsular Malaysia.

, a new species of Primulaceae from Peninsular Malaysia, is described and illustrated. The new species is assignable into subgenus (§) on account of specialised lateral reproductive branches bearing a terminal inflorescence subtended by foliose bracts. Morphologically, the new species mostly resembles in having elliptic leaves.

Interaction of Substrates with γ-Secretase at the Level of Individual Transmembrane Helices-A Methodological Approach.

Intramembrane proteases, such as γ secretase, typically recruit multiple substrates from an excess of single-span membrane proteins. It is currently unclear to which extent substrate recognition depends on specific interactions of their transmembrane domains (TMDs) with TMDs of a protease. Here, we investigated a large number of potential pairwise interactions between TMDs of γ secretase and a diverse set of its substrates using two different configurations of BLaTM, a genetic reporter system.