Introduction: Physiological and biochemical processes in the human body occur in a specific order and show rhythmic variability. Time dependence characterizes the secretion of cortisol and dehydroepiandrosterone (DHEA). One-day fasting implies alternating fasting days and eating days.
View Article and Find Full Text PDFBackground: The aim of this study was to determine the effect of using an oxygen-enriched breathing mixture during controlled physical training on blood oxidative stress parameters and total phenolics (TP) concentrations in obese adult women. Methods: A prospective randomized controlled trial study included 60 women aged 19−68 with BMIs greater than 30 kg/m2. Patients were randomly assigned to the study group (n = 30), which received additional intervention in supplementing the breathing mixture with oxygen at the flow of 6 L/min during training sessions, and the control group (n = 30).
View Article and Find Full Text PDFIntroduction: Hereditary angioedema (HAE) is a rare inherited autosomal dominant disease caused by deficiency or dysfunction of C1 inhibitor (C1INH). Clinical symptoms include recurrent subcutaneous and submucosal angioedema of the internal organs. Abdominal attacks affect more than 90% of patients, are often misdiagnosed and result in unnecessary surgical procedures.
View Article and Find Full Text PDFBackground: Physical activity undertaken in the treatment process additionally increases the oxygen demand of the working muscles. It seems interesting to see whether a delivery of an enriched respiratory mixture can have an impact on lower acidification of working muscles and oxygenation of tissues.
Objectives: To assess tissue saturation and the level of acidification at rest and during exercise while breathing atmospheric air or an oxygen-enriched mixture.
Hereditary angioedema (HAE) due to C1-inhibitor (C1-INH) deficiency is a rare disease characterized by recurrent swellings. This study aims to determine (i) the clinical characteristics of the HAE patient population from Poland, and (ii) real-life patients' treatment practices. A cross-sectional study involved 138 adult HAE patients (88 females, 50 males) treated in six regional HAE centers in Poland.
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