Publications by authors named "A Johanne van Ballegooijen"
Aims/hypothesis: Both manifestations of kidney disease in diabetes, reduced eGFR (ml/min per 1.73 m) and increased urinary albumin/creatinine ratio (UACR, mg/mmol), may increase the risk of specific CVD subtypes in adults with diabetes.
Methods: We assessed the prospective association between annually recorded measures of eGFR and UACR and the occurrence of myocardial infarction (MI), CHD, stroke, heart failure (HF) and cardiovascular mortality in 13,657 individuals with diabetes (53.
Article Synopsis
- This paper explores a randomized controlled trial designed to evaluate the effects of magnesium supplementation and phosphate-binding therapy on arterial stiffness and vascular calcification in patients with stage 3-4 chronic kidney disease (CKD).
- 180 patients will participate, receiving either magnesium citrate or a placebo, with or without the phosphate binder sucroferric oxyhydroxide, over a 24-week period.
- The trial's main goal is to measure changes in arterial stiffness, while secondary outcomes include markers of calcification and inflammation, along with exploratory PET scans for a subset of participants.
We investigated the prospective associations of body composition with cardiac structure and function and explored effect modification by sex and whether inflammation was a mediator in these associations. Total body (BF), trunk (TF) and leg fat (LF), and total lean mass (LM) were measured at baseline by a whole body DXA scan. Inflammatory biomarkers and echocardiographic measures were determined both at baseline and follow-up in the Hoorn Study (n = 321).
View Article and Find Full Text PDFBackground: Vitamin K is associated with reduced cardiovascular disease risk such as heart failure, possibly by carboxylation of matrix-gla protein (MGP), a potent inhibitor of vascular calcification. The relationship of vitamin K intake or status with cardiac structure and function is largely unknown. Therefore this study aims to investigate the prospective association of vitamin K status and intake with echocardiographic measures.
View Article and Find Full Text PDFBackground And Aims: This study aims to investigate the relationship of serum and dietary advanced glycation endproducts (AGEs) with cardiac function and structure after eight years of follow-up.
Methods And Results: We included 370 Hoorn Study participants (aged 66.4 ± 6.