Acute, febrile disease in a young person with no previous medical history is most often caused by infection. If disease progresses despite antimicrobial treatment vascular and collagen diseases should be taken into account in differential diagnosis We present a case of a young man, with lung infiltrations and cavities in the course of febrile illness. He was referred to our hospital with a suspicion of Wegener's granulomatosis after few days of ineffective antimicrobial therapy.
View Article and Find Full Text PDFPleural empyema still comprises an important therapeutic problem despite the availability of effective antibiotic therapy. This disorder is characterised by 20% mortality rate. Moreover, the involvement of multi-drug resistant bacterial strains may pose a risk of a nosocomial spread to other hospitalised patients.
View Article and Find Full Text PDFProper identification of the organism and determination of their sensitivity to antimicrobial agents, is the most important part of the management of patients with symptoms of respiratory system infections. In the case of pulmonary infections, the utility of sputum for diagnosing the cause of lower respiratory tract infections seems to be limited. In the patients receiving antibiotics, there is a high rate of colonization of the upper respiratory tract that may lead to the overgrowth of one or an other pathogen, making it more abundant in the upper than an lower respiratory tract.
View Article and Find Full Text PDFThe aim of the study was to establish the frequency of occurrence of bacterial pathogens with beta-lactamase activity, and pattern of resistance among aerobic and anaerobic strains isolated from: respiratory tract, urinary tract, skin and soft tissues (hospitalized patients) and throat swabs (ambulatory patients). The study was conducted in 1994 year in 6 bacteriological laboratories in four Polish towns (Warszawa, Kraków, Katowice, Gdańsk) according to the protocol. Sensitivity of bacteria was tested by the disc method on the Müeller-Hinton agar or chocolate agar according to NCCLS, activity of beta-lactamase was tested with nitrocephin.
View Article and Find Full Text PDFAnalysis of drug-sensitiveness of 822 M. tuberculosis strains isolated from patients with pulmonary tuberculosis treated in the Institute of Tuberculosis and Lung Diseases and in Pediatric Clinic of Medical Academy in Warsaw in 1982-1991 years was performed for isoniazid (INH), streptomycin (SM), rifampicin (RMP) and ethambutol (EMB). Drug sensitivity test was done on a basis of complexed proportional method according to Conethi and resistance index method according to Mitchinson.
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