Comparing visual inspection methods for parenteral products in hospital pharmacy: between reliability, cost, and operator formation considerations.

Introduction: The COVID-19 pandemic has led to unforeseen and novel manifestations, as illustrated by the management of drug shortages through the development of hospital production of sterile pharmaceutical preparations (P2S). Visual inspection of P2S is a release control whose methods are described in monographs of the European Pharmacopoeia (2.9.

Martian Magmatic Clay Minerals Forming Vesicles: Perfect Niches for Emerging Life?

Mars was habitable in its early history, but the consensus is that it is quite inhospitable today, in particular because its modern climate cannot support stable liquid water at the surface. Here, we report the presence of magmatic Fe/Mg clay minerals within the mesostasis of the martian meteorite NWA 5790, an unaltered 1.3 Ga nakhlite archetypal of the martian crust.

[Hepatitis B and pregnancy. Part 2. Nine practical issues about delivery and neonatal care].

In France, the hepatitis B maternal-fetal transmission prevention strategy is based on serovaccination at birth. Serum therapy is to inject 30IU/kg of anti-HBs specific immunoglobulins of human origin in the first hours of life, which in practice corresponds to 1ml or 100IU. Vaccination should also be performed during the first hours of life, and a new injection should be performed at 1month and 6months.

[Hepatitis B and pregnancy. Part 1. Thirteen practical issues in antenatal period].

In France, the prevalence of chronic hepatitis B is about 1% in pregnant women (usually asymptomatic carriers of HBsAg). The risk of maternal-fetal transmission of hepatitis B is particularly high when viral load measured by PCR is higher in mothers (above 7 log) or HBeAg is present. In case of maternal-fetal transmission of hepatitis B, the risk to the newborn of developing subsequent chronic hepatitis B is very high (90%), with long-term complications such as cirrhosis and hepatocellular carcinoma.

Tissint martian meteorite: a fresh look at the interior, surface, and atmosphere of Mars.

Tissint (Morocco) is the fifth martian meteorite collected after it was witnessed falling to Earth. Our integrated mineralogical, petrological, and geochemical study shows that it is a depleted picritic shergottite similar to EETA79001A. Highly magnesian olivine and abundant glass containing martian atmosphere are present in Tissint.