Publications by authors named "A Jama"

: Colorectal cancer (CRC) ranks as the third most prevalent cancer globally and is the third leading cause of cancer-related deaths. In 2020 alone, there were over 1.9 million new cases of CRC and nearly 0.

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Background: Abdominal pregnancy is a rare but, serious obstetric condition that has continued to pose difficulties in its diagnosis and management. The clinical presentation takes various forms, mostly nonspecific, leading to the delay in diagnosis and management. With a high degree of suspicion, the diagnosis can be made by an abdominal ultrasound particularly in the early trimesters.

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The impact of LRRK2 variants on the risk of Parkinson's disease in Egyptians remains unknown. We examined 1210 Egyptians (611 PD patients and 599 controls) from 16 governorates across Egypt for 12 LRRK2 pathogenic variants. The p.

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Article Synopsis
  • Genome-wide association studies (GWAS) have effectively identified disease-related genetic markers and antimicrobial resistance factors in bacterial pathogens, using a new phenotype-to-genotype approach to analyze multiple traits simultaneously.
  • Researchers examined 163 specific bacterial isolates for 11 traits, revealing significant differences in eight traits between disease subgroups and candidate genes linked to survival advantages.
  • The study highlights the importance of integrating high-throughput phenotypic testing with genomic analysis, successfully identifying key genetic determinants that contribute to the behavior and pathogenicity of bacterial pathogens.
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Recent advancements in targeted therapies for non-small-cell lung cancer (NSCLC), specifically focusing on epidermal growth factor receptor (EGFR) mutations, have revolutionized treatment strategies. Osimertinib, an approved therapy for metastatic NSCLC with EGFR mutations, highlights remarkable efficacy but also harbors the potential for severe adverse events, whose rarity or lack of precedence may mask their criticality. This article delves into the exploration of adverse events linked to osimertinib, shedding light on a rare yet life-threatening occurrence: severe myelosuppression.

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