Publications by authors named "A Jaensch"
Article Synopsis
- Geriatricians are playing a larger role in treating fragility fractures, especially in Germany, where hospitals can be certified as 'geriatric trauma centers' if they meet certain standards for orthogeriatric co-management (OGCM).
- A study analyzed the prescription frequencies of anti-osteoporotic drugs and vitamin D among nearly 200,000 patients aged 80 and older, comparing hospitals with no OGCM, those with OGCM, and certified OGCM.
- Results showed that hospitals with certified OGCM had the highest rates of prescriptions for these medications following fractures, indicating that better management practices lead to improved patient care.
Short-chain fatty acids (SCFAs) are immunomodulatory compounds produced by the microbiome through dietary fiber fermentation. Although generally considered beneficial for gut health, patients suffering from inflammatory bowel disease (IBD) display poor tolerance to fiber-rich diets, suggesting that SCFAs may have contrary effects under inflammatory conditions. To investigate this, we examined the effect of SCFAs on human macrophages in the presence of Toll-like receptor (TLR) agonists.
View Article and Find Full Text PDFBackground: Orthogeriatric co-management (OGCM) addresses the special needs of geriatric fracture patients. Most of the research on OGCM focused on hip fractures while results concerning other severe fractures are rare. We conducted a health-economic evaluation of OGCM for pelvic and vertebral fractures.
View Article and Find Full Text PDFArticle Synopsis
- The study examined the link between long-term air pollution exposure and end-stage kidney disease (ESKD) in two large European cohorts, highlighting the burden ESKD poses on patients and healthcare systems.
- In the Austrian cohort (VHM&PP), increased black carbon and nitrogen dioxide showed potential associations with ESKD, but findings were not statistically significant.
- Conversely, in the Italian cohort (RoLS), fine particulate matter was significantly associated with ESKD, indicating that the impact of air pollution on kidney health may differ based on the specific pollutants present in different regions.