Publications by authors named "A Jaccard"
Article Synopsis
- * Quick diagnosis and treatment of kidney problems in these patients are crucial, with therapies focusing on hydration, correcting contributing factors, and administering effective anti-myeloma drugs while considering the patient's kidney function and overall health.
- * Advanced treatments like plasma exchange may improve kidney recovery in severe cases, and newer combinations of medications show promise, with the possibility of kidney transplantation for some patients in the future.
Kidney disease is a common complication of monoclonal immunoglobulin (MIg)-secreting B-cell disorders and predominantly occurs in patients who do not meet the criteria for an overt hematological disease. To distinguish this situation from monoclonal gammopathy of undetermined significance, which lacks organ damage, the term monoclonal gammopathy of renal significance (MGRS) was introduced to depict the association of a small, otherwise indolent B-cell clone, with renal disease induced by the secreted MIg. The spectrum of renal disorders in MGRS is wide, encompassing both tubular and glomerular disorders, classified according to the composition of deposits and their ultrastructural pattern of organization.
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