Publications by authors named "A JOB"
With advances in cancer treatment, long-term survival rates have improved in recent decades, resulting in extended life expectancies for many patients. This progress brings substantial challenges, however, particularly in terms of the costs associated with cancer care. The financial burden, often considerable, poses difficulties for older adults with cancer and their caregivers.
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- Cushing's syndrome (CS) has significant neurocognitive and psychiatric impacts that reduce quality of life, prompting a systematic review of affected patients compared to healthy controls and those with non-functioning pituitary adenomas (NFPA).
- The study analyzed 40 eligible research papers, identifying 2603 participants, 45.2% of whom had Cushing's disease (CD), with a focus on their psychiatric symptoms and cognitive performance before and after surgical treatment.
- Findings indicate that higher baseline cortisol levels in patients with CS correlate with worse cognitive function, even post-surgery, and prolonged periods of uncontrolled CS may lead to persistent cognitive challenges.
The incorporation of nitric oxide (NO) into polymeric matrices minimizes degradation and facilitates controlled release. This optimization increases the field of application of NO, in dressings, food protective films, and implant devices, among others. This work presents an economical and easy way to manufacture bioactive nitric oxide-releasing polymer (BioNOR-P) and evaluates its bactericidal and antioxidant activity (AA), mechanical behavior, cytotoxicity, and genotoxicity, seeking future use in different applications.
View Article and Find Full Text PDFIn recent years, mitochondria have gained significant interest in the field of biomedical research due to their impact on aging, human health, and other advanced findings in metabolic functions. The latest finding shows that metabolic interventions are a leading cause of several diseases, which has sparked interest in finding new therapeutic treatments. Apart from this, the unique inheritance of genetic material from mother to offspring can help scientists find ways to prevent mitochondrial inherited diseases.
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