Publications by authors named "A J van Hasselt"
Article Synopsis
- A follow-up screening study evaluated the long-term significance of positive Epstein–Barr virus (EBV) DNA results in individuals previously screened for nasopharyngeal cancer (NPC).
- Out of 17,838 participants rescreened, 423 had persistently detectable EBV DNA, which led to the identification of 24 cases of NPC, with a significantly higher proportion being early-stage cancers compared to historical data.
- The results indicate that individuals with detectable EBV DNA were considerably more likely to be diagnosed with NPC in subsequent screenings, highlighting the potential of EBV DNA analysis for improvement in early detection and survival rates.
Background: The prevalence of gastroesophageal reflux disease (GERD) and laryngopharyngeal reflux (LPR) in post-irradiated patients with nasopharyngeal carcinoma (NPC) is unknown.
Materials And Methods: In a cross-sectional study, 31 NPC and 12 control patients completed questionnaires for GERD/LPR before esophageal manometry and 24-h pH monitoring. The DeMeester score and reflux finding score (RFS) were used to define GERD and LPR, respectively.
Article Synopsis
- A study was conducted to evaluate a short, contrast-free MRI for detecting nasopharyngeal carcinoma (NPC) in patients screened positive for Epstein-Barr virus (EBV) DNA.
- Among 354 patients, MRI identified additional NPC cases that were missed by endoscopy, with high sensitivity and specificity for detecting the cancer.
- The results suggest that MRI can enhance NPC screening programs by finding cases that traditional methods might overlook, improving early detection and reducing the risk of missed diagnoses.
Background: Exercise-based swallowing training (EBST) and transcutaneous neuromuscular electrical stimulation (TNMES) are common modalities used to treat late dysphagia after radiotherapy for nasopharyngeal carcinoma (NPC). We aimed to investigate and compare the efficacies of EBST and TNMES as proactive treatments administered early after radiotherapy.
Methods: Patients with early post-radiotherapy NPC ( = 120) underwent either TNMES or EBST.
Objective: The primary aim of this study was to assess to what extent 99mTc-HDP Single photon emission computed tomography/computed tomography (SPECT/CT) will lead to change of diagnosis and treatment, in patients with suspected foot and ankle osteoarthritis (OA). Secondary aim was to assess the intraobserver variability.
Methods: Retrospectively 107 patients, with suspected foot and/or ankle OA of which a SPECT/CT was made, were included for analysis.