Publications by authors named "A J Ying"
Background: The efficacy of microwave ablation (MWA) and radiofrequency ablation (RFA) in hepatocellular carcinoma (HCC) patients with decompensated cirrhosis remains unclear.
Methods: A total of 315 patients with decompensated cirrhosis and HCC who underwent MWA or RFA were recruited. Recurrence beyond the Milan criteria (RBM), local tumor progression (LTP), overall survival (OS), and complications were evaluated and compared.
Doubly robust estimation under covariate-induced dependent left truncation.
Biometrika
September 2024
In prevalent cohort studies with follow-up, the time-to-event outcome is subject to left truncation leading to selection bias. For estimation of the distribution of the time to event, conventional methods adjusting for left truncation tend to rely on the quasi-independence assumption that the truncation time and the event time are independent on the observed region. This assumption is violated when there is dependence between the truncation time and the event time, possibly induced by measured covariates.
View Article and Find Full Text PDFBackground: Definitive radiotherapy (dRT) has been shown to be an effective option for patients with oligometastatic and oligoprogressive cancers; however, this approach has not been well-studied in metastatic thyroid cancer.
Methods: This retrospective cohort included 119 patients with oligometastatic (34%) and oligoprogressive (66%) metastatic thyroid cancer treated from 2005 to 2024 with 207 dRT courses for 344 sites (50% thoracic, 37% bone, 7.5% brain, 4% abdominopelvic, and 1.
Carbene-metal-amide (CMA) complexes are appealing emitters for organic light-emitting diodes (OLEDs). However, little is known about silver(i)-CMA complexes, particularly electroluminescent ones. Here we report a series of Ag(i)-CMA complexes prepared using benzothiophene-fused carbazole derivatives as amide ligands.
View Article and Find Full Text PDFArticle Synopsis
- - Eye drops are being developed as a promising non-invasive treatment for diseases affecting the back of the eye, but their effectiveness is challenged by various eye barriers.
- - Researchers propose using a single molecule nanomedicine called sulfonated azocalix[4]arene (SAC4A) to improve drug delivery, highlighted by its small size, negative charge, and ability to release drugs in low-oxygen conditions.
- - A study demonstrated that SAC4A could effectively deliver the drug sunitinib to treat wet age-related macular degeneration (wAMD), increasing the amount of drug reaching the targeted eye tissue significantly and enhancing its treatment effects.