Occupation and larynx and hypopharynx cancer: a job-exposure matrix approach in an international case-control study in France, Italy, Spain and Switzerland.

Objective: To investigate the effect of exposure to occupational agents on the risk of hypopharyngeal/laryngeal cancer.

Methods: Case-control study conducted during 1979-1982 in six centres in South Europe. An occupational history and information on exposure to non-occupational factors were collected for 1010 male cases of hypopharyngeal/ laryngeal cancer as well as for 2176 population controls.

Occupation and larynx and hypopharynx cancer: an international case-control study in France, Italy, Spain, and Switzerland.

Objective: To estimate risks for laryngeal/hypopharyngeal cancer associated with occupational titles and industrial activities.

Methods: A multicentre population-based case-control study was conducted in the early 1980s in six southern European areas. Analyses included 1010 male cases and 2176 controls.

[Alcohol and cancer].

Regular consumption of alcoholic beverages increases the risk of cancer in the upper aero-digestive tract and in the liver. There is a dose-response relationship and the effects are combined with those of tobacco, according to a multiplicative model. The biologic mechanisms are unclear.

Nutrient intake patterns and gastric cancer risk: a case-control study in Belgium.

A case-control study on gastric cancer risk in relation to nutrient composition of diet was conducted in the 2 Belgian provinces of Oost-Vlaanderen and Liège as part of a large epidemiological study on cancers of the digestive tract, also including colorectal cancer. The statistical analysis was carried out on a total of 301 men and women aged 35-74 years with histologically confirmed stomach tumors and 2,851 population controls. Dietary intake assessments were obtained by interview, using a dietary history questionnaire.

Incidence of tobacco and alcohol-related cancers in western Europe.

The relative importance of the tobacco and alcohol-related cancer burden varies across countries. Within western Europe, the incidence of lung cancer has a clearly different geographical pattern to the incidence of alcohol-related cancer. Each country's public health policies should take into account its own tobacco and alcohol-related morbidities.